Why get genetic testing for familial chylomicronemia syndrome (FCS)?

A diagnosis confirmed by testing may improve the management of FCS.

Since FCS is a rare genetic disorder, patients with symptoms or a clinical diagnosis of FCS may benefit from a test that checks to see if they have one or more of the genes that causes FCS. Confirming a diagnosis of FCS can help guide medical management by your healthcare professionals (HCPs).^1,12

Benefit of genetic testing for FCS

Genetic testing looks for variants in a person’s genes that may cause FCS.^1,43 Healthcare professionals may use genetic tests for two main reasons:

• Confirming an FCS diagnosis: Genetic testing can help people suspected of having or clinically diagnosed with FCS see if they have disease-causing variants in FCS-related genes. In this case, the test may confirm their disease.¹

• Guide treatment and management: Finding out that FCS is the right diagnosis is important because it may help healthcare professionals make lifestyle recommendations and referrals to specialists, such as a lipidologist.¹⁵

Eligibility for testing

While genetic testing is available clinically at commercial laboratories, cost and access may be factors to consider.

The FCS Genetic Testing program is sponsored by Ionis Pharmaceuticals and available to certain qualifying patients. Talk with your HCP to see if you qualify for the program. You may qualify if you have:

• Extremely high triglyceride levels (more than 880 mg/dL or 10 mmol/L), on two fasting blood tests in a row.
• No other known causes of high TG levels.

Get your questions answered 

The FCS Genetic Testing program has partnered with Genome Medical to provide information on FCS, as well as support surrounding the genetic testing process. 

The FCS Genetic Testing program offers genetic counseling through Genome Medical, an independent genetic counseling service.

Call +1.888.478.1494 to learn more.