Man sitting on wheel

About
triglycerides

Actor portrayal; not an actual person with very high triglycerides.

What are Triglycerides?

Triglycerides are a type of fat your body uses to store energy. Another type of fat is cholesterol, which the body uses to build cells and make hormones.

Fork and knife icon. Triglycerides come from the food we eat and are also made within the body itself.
Blood vessels icon. Triglycerides travel in the bloodstream to provide energy throughout the body.

While triglycerides play an important role in your body, they can raise your risk for certain health problems if they get too high—like pancreatitis, a painful inflammation of the pancreas, and heart disease.

What does your
triglyceride level mean?

Doctors measure triglycerides and other fats, like cholesterol, through a blood test called a lipid panel or lipid profile. 

Actor portrayal of a patient with very high triglycerides.

Actor portrayal; not an actual person with very high triglycerides.

Scroll to see what a normal triglyceride level is and how your health can be impacted if your level gets too high.

Normal
Triglyceride levels

Below 150 mg/dL is considered to be a healthy range for triglycerides in the blood.

High
Triglyceride levels

150-499 mg/dL is considered elevated or high.

Having high triglycerides can raise your risk of heart disease and can contribute to conditions such as fatty liver disease.

Very high
Triglyceride levels

500-879 mg/dL is considered very high. Your doctor may refer to it as severe hypertriglyceridemia.

Having very high triglycerides can greatly increase your risk of pancreatitis and heart disease and can contribute to conditions like fatty liver disease.

Extremely high
Triglyceride levels

880 mg/dL or higher is considered
extremely high.

Triglycerides that are 880 mg/dL or higher can seriously increase your risk for pancreatitis. This level can also be related to a rare genetic condition called familial chylomicronemia syndrome (FCS) that can cause triglycerides to be 10 to 100 times above typical levels.

Lowering the risk of pancreatitis is one of the most important reasons for people with very high triglycerides to keep their levels under control.

What are the symptoms of VERY HIGH triglycerides?

Very high triglycerides don’t just raise your risk for serious health problems. They can also affect how you feel every day. 

Some people with very high triglycerides don't notice any symptoms. But not having symptoms doesn't mean everything is fine. Others may experience:

Icon of a person with tense posture, with stress lines radiating outward. Anxiety
Icon of a side profile of a head with a cloud inside. Brain fog
Icon of a stomach with a lightning bolt inside. Stomach pain
Icon of a person with slumped shoulders and a depleting battery above their head. Fatigue
Icon of a side profile of a head, with a brain and a question mark inside. Difficulty remembering things
Icon of a side profile of a head with a tangled scribble inside. Difficulty thinking
Icon of a person with their head in their hands, with vertical lines around them to suggest emotional heaviness or sadness. Depression
Icon of a side profile of a head with a warning symbol inside. Difficulty paying attention
Icon of intestines with lines radiating outward. Diarrhea

Whether you experience symptoms or not, it's important to manage your triglycerides
to help reduce the risk of serious health problems.

Talking to your doctor about your triglycerides

If you have very high triglycerides (500 mg/dL or above), it’s really important to work with your doctor to make a plan. Bring this guide to your next appointment to help you ask the right questions and make the most of your conversation.

Download the discussion guide

What causes VERY HIGH TRIGLYCERIDES?

Very high triglycerides are typically caused by a combination of many factors and differ from person to person. Finding what's behind your very high triglycerides can help you and your healthcare team better manage your triglyceride levels with appropriate lifestyle changes and medications.

Lifestyle

Very high triglycerides can be caused by:

Foods high in fat
Sugary foods and drinks
Low physical activity
Alcohol

HEALTH CONDITIONS

Some health conditions that can affect triglyceride levels:

CLICK EACH ICON TO LEARN MORE

A shadow of a person surrounded by icons of some health conditions that can cause very high triglycerides.

Metabolic issues
Hormone-related conditions
Inflammatory and autoimmune conditions
Liver and kidney problems

MEDICATIONS

Common medications that may raise your triglycerides:

  • Certain water pills such as thiazide and loop diuretics used to treat swelling or high blood pressure
  • Medications called beta-blockers for blood pressure or heart conditions
  • Birth control pills
  • Hormone replacement therapy (HRT)
  • Some acne treatments such as isotretinoin
  • Steroid medication used to treat asthma or arthritis
  • Medications that lower cholesterol by removing bile acids
  • Protease inhibitors used to treat HIV
  • Certain immune-suppressing treatments such as sirolimus
  • Some medications used for mental health conditions like anxiety or depression
White pills pouring into a hand from a green pill bottle.

Some medications can raise your triglycerides. Before making changes to your medications, talk to your doctor or healthcare team.

Genetic CAUSES

For some people, genetics may partly explain why they have extremely high triglycerides. Some genetic causes for extremely high triglycerides include:

  • Familial chylomicronemia syndrome (FCS)
  • Multifactorial chylomicronemia syndrome (MCS)

Even if extremely high triglycerides are caused by genetics, eating healthy, being active, and taking prescribed medications are still important for managing triglycerides.

About FCS

FCS is a rare genetic condition that can cause triglycerides to be above 880 mg/dL, and can be 10 to 100 times the normal levels.

Learn about FCS

Learn how triglycerides are managed


Find out how you and your doctor can work together to manage your triglycerides and improve your overall health.

MANAGING triglycerides